Which medication should be administered intravenously for status epilepticus?

In cases of status epilepticus, Lorazepam is the preferred medication for intravenous administration due to its rapid onset of action and effective anticonvulsant properties. It enhances the effects of the neurotransmitter GABA (gamma-aminobutyric acid), which helps to stop seizures quickly and stabilize the patient's neurological status. Lorazepam is particularly favored because it can be administered safely in an emergency setting and is associated with fewer cardiovascular side effects compared to other options.

Other medications listed may have clinical use in different contexts but are not optimal for immediate management of status epilepticus. Dexamethasone is a corticosteroid used primarily in inflammatory conditions and does not have anticonvulsant properties. Phenobarbital can be effective but is typically utilized in a more delayed manner due to its longer duration of action and potential side effects. Clozapine is an atypical antipsychotic medication and does not function to control seizures and therefore would not be appropriate for this emergency situation. Thus, Lorazepam stands out as the first-line drug for the acute treatment of status epilepticus when intravenous administration is required.