What is the initial IPAP setting for NPPV?

The recommended initial setting for inspiratory positive airway pressure (IPAP) in non-invasive positive pressure ventilation (NPPV) is typically between 10 and 15 cm H2O. This range is appropriate as it provides sufficient ventilatory support while minimizing the risk of discomfort or excessive pressure that could lead to complications.

Setting the IPAP too low may not provide adequate ventilation, especially in patients with significant respiratory distress or failure, whereas settings too high could lead to discomfort and decreased patient compliance. The range of 10 to 15 cm H2O balances the need for effective ventilation and patient tolerance, thereby facilitating successful long-term use of NPPV. It is common to start lower within this range and adjust according to the patient's response to treatment.