Long-acting calcium channel blockers are appropriate for which purpose in STEMI patients?

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Long-acting calcium channel blockers are used appropriately as secondary therapy for recurrent myocardial ischemia in STEMI patients. In the context of STEMI, initial management typically focuses on restoring coronary perfusion, often using antiplatelet agents, anticoagulants, and reperfusion therapy (such as PCI or thrombolytics). Once the acute phase has been managed, some patients may experience ongoing symptoms of myocardial ischemia, which long-acting calcium channel blockers can help alleviate. They work by relaxing vascular smooth muscle, thereby reducing myocardial oxygen demand and improving blood flow to ischemic areas.

This makes them suitable for patients who have persistent angina or other ischemic symptoms after the acute event has been handled. Long-acting calcium channel blockers are not the first choice as initial therapy due to the immediate need to address the occlusion in the coronary arteries, and they are not indicated for immediate pain relief or for long-term management of heart failure specifically in the acute context of STEMI.

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