After fibrinolysis, how long should heparin be used to maintain vessel patency?

Heparin is utilized following fibrinolytic therapy to prevent reocclusion of the treated vessel. The recommendation for heparin use is generally for a duration of 48 hours after fibrinolysis. This timeframe is important as it allows for the stabilization of the thrombolytic effect and ensures that the risk of clot reformation is minimized during this critical period.

The 48-hour duration balances the need for maintaining vessel patency while also considering the risks associated with prolonged anticoagulation therapy. After this period, careful assessment of the patient’s condition and the risk factors for thrombosis will guide further anticoagulation management, which may include transitioning to other forms of anticoagulants depending on the clinical scenario.

Using shorter or longer durations may not adequately address the need for prevention of complications, thereby making the 48-hour period a standard practice in clinical settings.